| 產(chǎn)品編號(hào) | bs-19980R-Cy5 |
| 英文名稱(chēng)1 | Rabbit Anti-PRA1/PRAF1/Cy5 Conjugated antibody |
| 中文名稱(chēng) | Cy5標(biāo)記的PRA1蛋白抗體 |
| 別 名 | PRA1 domain family 1; PRA1 family protein 1; PRAF1; PRAF1_HUMAN; prenylated Rab acceptor 1; Prenylated Rab acceptor protein 1; Rab acceptor 1 (prenylated); RABAC1; YIP3. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 21kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PRA1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
Function: General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI. Subunit: Homodimer. Interacts with VAMP2 (synaptobrevin-2), GDI1,and PCLO (By similarity). Interacts specifically with prenylated Rab proteins; strongly with RAB4B, RAB5A and RAB5C, and weakly with RAB4A, RAB6, RAB7A, RAB17 and RAB22. Interacts with NDRG1. Subcellular Location: Cell membrane. Cytoplasm. Golgi apparatus. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle. According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles. Tissue Specificity: Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach. DISEASE: In fetal tissues, it is more abundant in kidney and lung. Similarity: Belongs to the PRA1 family. Database links: Entrez Gene: 10567 Human Entrez Gene: 14470 Mouse Omim: 604925 Human SwissProt: Q9UI14 Human SwissProt: Q9Z0S9 Mouse Unigene: 11417 Human Unigene: 22473 Mouse Unigene: 25604 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
