| 產(chǎn)品編號 | bs-19240R-BF488 |
| 英文名稱1 | Rabbit Anti-CHRNA5/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的煙堿型乙酰膽堿受體α5抗體 |
| 別 名 | Acetylcholine receptor nicotinic alpha 5 (neuronal); ACHA5_HUMAN; Cholinergic receptor neuronal nicotinic alpha polypeptide 5; Cholinergic receptor nicotinic alpha 5; Cholinergic receptor nicotinic alpha polypeptide 5; CHRNA 5; CHRNA5; LNCR2; NACHRA 5; NACHRA5; Neuronal acetylcholine receptor subunit alpha 5; Neuronal acetylcholine receptor subunit alpha-5; Neuronal nicotinic acetylcholine receptor alpha 5 subunit; Neuronal nicotinic acetylcholine receptor, alpha5 subunit; OTTHUMP00000185019. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 免疫學(xué) 神經(jīng)生物學(xué) 細胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 51kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CHRNA5 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).[provided by RefSeq, Jun 2010] Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Subcellular Location: Cell junction > synapse > postsynaptic cell membrane. Cell membrane. Tissue Specificity: High expression level is found in brain, testis, liver and kidney. Weak expression in spleen, leukocytes, small intestine and colon Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-5/CHRNA5 sub-subfamily. Database links: Entrez Gene: 386577 Chicken Entrez Gene: 619369 Chimpanzee Entrez Gene: 1138 Human Omim: 118505 Human SwissProt: P26152 Chicken SwissProt: Q5IS51 Chimpanzee SwissProt: P30532 Human Unigene: 1614 Human Unigene: 719767 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
