| 產(chǎn)品編號 | bs-12173R-APC |
| 英文名稱1 | Rabbit Anti-KCNF1/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的電壓門控性鉀通道蛋白亞基kv5.1抗體 |
| 別 名 | IK 8; IK8; KCNF 1; KCNF; Kcnf1; KCNF1_HUMAN; kH 1; kH1; KV5.1; Potassium voltage-gated channel subfamily F member 1; MGC33316; Potassium channel KH1; Potassium channel Kv5.1; Potassium voltage gated channel subfamily F member 1; Potassium voltage-gated channel subfamily F member 1; Voltage gated potassium channel subunit Kv5.1; Voltage-gated potassium channel subunit Kv5.1. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 通道蛋白 細(xì)胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 56kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNF1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas. Function: Putative voltage-gated potassium channel. Subunit: Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1. Subcellular Location: Membrane. Tissue Specificity: Detected in heart, brain, liver, skeletal muscle, kidney and pancreas. Similarity: Belongs to the potassium channel family. F (TC 1.A.1.2) subfamily. Kv5.1/KCNF1 sub-subfamily. Database links: Entrez Gene: 3754 Human Entrez Gene: 382571 Mouse Omim: 603787 Human SwissProt: Q9H3M0 Human SwissProt: Q7TSH7 Mouse Unigene: 23735 Human Unigene: 40173 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
