| 產(chǎn)品編號(hào) | bs-12324R-BF488 |
| 英文名稱1 | Rabbit Anti-PTCHD2/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的多通道膜蛋白PTCHD2抗體 |
| 別 名 | DISP3; Dispatched, drosophila, homolog of, 3; G630052C06Rik; hCG_24779; KIAA1337; Patched domain-containing protein 2; Protein dispatched homolog 3; Ptchd2; PTHD2_HUMAN; RGD1305820; RND-type protein RNDEu-2; RNDEu-2; patched domain containing 2; RP23-157B15.1; PTCHD2. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 通道蛋白 新陳代謝 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 153 kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human PTCHD2/DISP3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Tissue Specificity: Expressed in brain and testis. Similarity: Belongs to the patched family. Contains 1 SSD (sterol-sensing) domain. Database links: Entrez Gene: 57540 Human Omim: 611251 Human SwissProt: Q9P2K9 Human Unigene: 202355 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
