| 產(chǎn)品編號(hào) | bs-6180R-BF350 |
| 英文名稱1 | Rabbit Anti-Rab3A+Rab3B+Rab3C+Rab3D/BF350 Conjugated antibody |
| 中文名稱 | BF350標(biāo)記的ras癌基因家族Rab3A--Rab3D抗體 |
| 別 名 | RAB3A; RAB3A member RAS oncogene family; RAB3B; RAB3B member RAS oncogene family; RAB3C; RAB3C member RAS oncogene family; RAB3D member RAS oncogene family; RAD3D; Ras related protein Rab 3A; Ras related protein Rab 3B; Ras related protein Rab 3C; Ras related protein Rab 3D; D2 2; Glioblastoma overexpressed; GOV; RAB16. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 G蛋白偶聯(lián)受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Rat, (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 24-27kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Rab3A+Rab3B+Rab3C+Rab3D |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has four known isoforms: 3A, 3B, 3C and 3D. These proteins are expressed in the highest concentration in the brain and endocrine tissues and are involved in regulated exocytosis of hormones and neurotransmitters. Specifically Rab3's are thought to play a role in presynaptic vesicle trafficking and priming. Function: Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. Subunit: Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A and RPH3AL. Interacts with the exocyst complex through SEC15. Binds SYTL4 and RIMS1. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side. Tissue Specificity: Specifically expressed in brain. Similarity: Belongs to the small GTPase superfamily. Rab family. Database links: Entrez Gene: 115827 Human Entrez Gene: 5864 Human Entrez Gene: 5865 Human Entrez Gene: 9545 Human Entrez Gene: 19339 Mouse Entrez Gene: 19340 Mouse Entrez Gene: 67295 Mouse Entrez Gene: 69908 Mouse Entrez Gene: 399230 Xenopus laevis Entrez Gene: 495404 Xenopus laevis Omim: 179490 Human Omim: 179510 Human Omim: 604350 Human SwissProt: O95716 Human SwissProt: P20336 Human SwissProt: P20337 Human SwissProt: Q5VUL2 Human SwissProt: Q96E17 Human SwissProt: P35276 Mouse SwissProt: P62823 Mouse SwissProt: P63011 Mouse SwissProt: Q0PD62 Mouse SwissProt: Q0PD63 Mouse SwissProt: Q9CZT8 Mouse SwissProt: Q9JME6 Mouse SwissProt: Q3KQA5 Xenopus laevis Unigene: 123072 Human Unigene: 27744 Human Unigene: 482173 Human Unigene: 8036 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
