產(chǎn)品編號(hào) | IHC0533M |
英文名稱 | Mouse eIF4E Ready-To-Use IHC Kit |
中文名稱 | 小鼠真核翻譯起始因子4E即用型免疫組化試劑盒 |
別 名 | AUTS19; CBP; EG668879; eIF-4E; EIF4E; Eif4e-ps; EIF4E1; EIF4EL1; EIF4F; If4e; eIF-4E; eukaryotic translation initiation factor 4E; Messanger RNA Cap Binding Protein eIF 4E; IF4E_HUMAN |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G. SWISS: P06730 Gene ID: 1977 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Mouse stomach tissue slide using IHC0533M (Mouse eIF4E Kit).
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