| 產(chǎn)品編號(hào) | IHC0505R |
| 英文名稱 | Rat FOXL2 Ready-To-Use IHC Kit |
| 中文名稱 | 大鼠叉頭蛋白L2即用型免疫組化試劑盒 |
| 別 名 | AU045128; BPES; BPES1; FOXL2; PFRK; PINTO; POF3 |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
FOXL2 is a winged helix/forkhead transcription factor that is highly conserved in human, goat, mouse, and certain aquatic species. Given its cross-species conservation, it appears to play a critical role evolutionarily, likely in ovarian differentiation in mammals and in ovarian somatic cell differentiation and in further follicle development and/or maintenance. Immunohistochemical data shows that FOXL2 is a nuclear protein specifically expressed in eyelids and in fetal and adult ovarian follicular cells. It does not undergo any major posttranslational modifications. FOXL2 is also found to be associated with blepharo-phimosis/ptosis/epicanthus inverses syndrome (BPES). There are two forms of BPES. Type I BPES shows eyelid abnormal-ities that are associated with ovarian failure. In type II BPES, only eyelid defects are found. Studies have shown that FOXL2 is expressed in the mesenchyme of developing mouse eyelids and in adult ovarian follicles. SWISS: P58012 Gene ID: 668 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Rat testis tissue slide using IHC0505R (Rat FOXL2 Kit).
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