產(chǎn)品編號(hào) | D62049 |
英文名稱 | 4-P-PDOT |
中文名稱 | |
別 名 | 4-phenyl-2- propionamidotetralin |
克 隆 號(hào) | |
CAS | 134865-74-0 |
理論分子量 | ?279.38 kDa |
檢測(cè)分子量 | |
保存條件 | -20℃ |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
4-P-PDOT is a potent, selective and affinity Melatonin receptor (MT2) antagonist. 4-P-PDOT is >300-fold more selective for MT2 than MT1. 4-P-PDOT significantly counteracts Melatonin-mediated antioxidant effects (GSH/GSSG ratio, phospho-ERK, Nrf2 nuclear translocation, Nrf2 DNA-binding activity) |