| 產(chǎn)品編號(hào) | D51578 |
| 英文名稱 | Brigatinib-analog |
| 中文名稱 | |
| 別 名 | ALK/EGFR抑制劑 |
| 克 隆 號(hào) | |
| CAS | 1197958-12-5 |
| 理論分子量 | 529.01 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Brigatinib-analog is an orally active, potent and selective anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) inhibitor. Brigatinib-analog is structurally related to Brigatinib (AP-26113). Brigatinib-analog binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and eventually inhibits tumor cell growth in susceptible tumor cells. |
| 產(chǎn)品圖片 |
外觀及包裝
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