產(chǎn)品編號 | D51572 |
英文名稱 | Sildenafil Citrate |
中文名稱 | |
別 名 | PDE5抑制劑 |
克 隆 號 | |
CAS | 171599-83-0 |
理論分子量 | 666.7 kDa |
檢測分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Sildenafil is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism. |