| 產(chǎn)品編號 | D51540 |
| 英文名稱 | LC3-mHTT-IN-AN1 |
| 中文名稱 | |
| 別 名 | LC3-mHTT抑制劑 |
| 克 隆 號 | |
| CAS | 486443-73-6 |
| 理論分子量 | 411.04 kDa |
| 檢測分子量 | |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
LC3-mHTT-IN-AN1 is a HTT-LC3 linker compound. LC3-mHTT-IN-AN1 interacts with both LC3 and mHTT, but not with the wild-type HTT protein. LC3-mHTT-IN-AN1 reduced mHTT levels in an allele-selective manner, and rescued disease-relevant phenotypes in cells and in vivo in fly and mouse models of Huntington's disease |
