產(chǎn)品編號(hào) | D51475 |
英文名稱 | SKL2001 |
中文名稱 | |
別 名 | Wnt/β-Catenin激動(dòng)劑 |
克 隆 號(hào) | |
CAS | 909089-13-0 |
理論分子量 | 286.29 kDa |
檢測(cè)分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
SKL2001 is a novel agonist of Wnt/β-catenin signaling pathway. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. SKL2001 inhibited proliferation of colon cancer cells cultured in 3D spheroid and induced them accumulation in the G0/G1 phase of the cell cycle with a reduced c-myc level. |