產(chǎn)品編號 | D51454 |
英文名稱 | LY3200882 |
中文名稱 | |
別 名 | TGF-β receptor I (ALK5)抑制劑 |
克 隆 號 | |
CAS | 1898283-02-7 |
理論分子量 | 435.52 kDa |
檢測分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
LY3200882 is an orally active TGFbeta inhibitor. LY3200882 targets transforming growth factor-beta (TGFb), with potential antineoplastic activity. Upon administration, LY3200882 specifically targets and binds to TGFb, which prevents both the binding of TGFb to its receptor TGFbR and TGFb-mediated signal transduction. This may lead to a reduction in TGFb-dependent proliferation of cancer cells. |