| 產(chǎn)品編號 | D51439 |
| 英文名稱 | Trimethylamine N-oxide |
| 中文名稱 | |
| 別 名 | ROS/NLRP3和TGF-β/smad2激活劑 |
| 克 隆 號 | |
| CAS | 1184-78-7 |
| 理論分子量 | 75.11 kDa |
| 檢測分子量 | |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway. |
