| 產(chǎn)品編號(hào) | D51413 |
| 英文名稱(chēng) | Y-39983 |
| 中文名稱(chēng) | |
| 別 名 | ROCK抑制劑 |
| 克 隆 號(hào) | |
| CAS | 199433-58-4 |
| 理論分子量 | 280.32 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Y-39983 (free base), also known as Y-33075, is a potent and selective inhibitor of ROCK family with IC50 value of 3.6nM for ROCK. Y-39983 attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination. Y-39983 downregulates RhoA/Rho-associated kinase expression during its promotion of axonal regeneration. Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats. |
