產(chǎn)品編號(hào) | D51320 |
英文名稱 | ROC-325 |
中文名稱 | |
別 名 | Autophagy抑制劑 |
克 隆 號(hào) | |
CAS | 1859141-26-6 |
理論分子量 | 503.06 kDa |
檢測(cè)分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
ROC-325 is an autophagy inhibitor. ROC-325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds. ROC-325 antagonized RCC growth and survival in an ATG5/7-dependent manner, induced apoptosis, and exhibited favorable selectivity. |