產(chǎn)品編號 | D51316 |
英文名稱 | UK-5099 |
中文名稱 | |
別 名 | MPC抑制劑 |
克 隆 號 | |
CAS | 56396-35-1 |
理論分子量 | 288.3 kDa |
檢測分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
UK-5099 is a specific and potent mitochondrial pyruvate carrier blocker (MCK blocker). The UK5099 treated cells showed significantly higher proportion of side population (SP) fraction and expressed higher levels of stemness markers Oct3/4 and Nanog. Chemosensitivity examinations revealed that the UK5099 treated cells became more resistant to chemotherapy compared to the non-treated cells. MPC blocker (UK5099) application may be an ideal model for Warburg effect studies |