產(chǎn)品編號(hào) | D51295 |
英文名稱 | Fenretinide |
中文名稱 | 維甲酰酚胺 |
別 名 | RAR激動(dòng)劑 |
克 隆 號(hào) | |
CAS | 65646-68-6 |
理論分子量 | 391.55 kDa |
檢測(cè)分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Fenretinide is an orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis-associated growth factors and their receptors and exhibits retinoid receptor-independent apoptotic properties. |