| 產(chǎn)品編號(hào) | D51286 |
| 英文名稱 | Apixaban |
| 中文名稱 | |
| 別 名 | Factor Xa抑制劑 |
| 克 隆 號(hào) | |
| CAS | 503612-47-3 |
| 理論分子量 | 459.5 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Apixaban, also known as BMS-56224701, is an anticoagulant for the treatment of venous thromboembolic events. Apixaban is a direct factor Xa inhibitor. Apixaban was approved in 2012. Apixaban is indicated for the following: (1) To lower the risk of stroke and embolism in patients with nonvalvular atrial fibrillation. (2) Deep vein thrombosis (DVT) prophylaxis. DVT's may lead to pulmonary embolism (PE) in knee or hip replacement surgery patients. (3) Treatment of both DVT and PE. (4) To reduce the risk of recurring DVT and PE after initial therapy. CAS：503612-47-3 分子式：C25H25N5O4 分子量：459.51 MDL：MFCD11977295 純度：≥99%（HPLC） 溶解性：溶于DMSO 作用靶點(diǎn)：Factor Xa; 作用通路：Metabolic Enzyme/Protease; 產(chǎn)品描述：阿哌沙班 (Apixaban) 是一種高度選擇性，可逆并具有口服活性分 凝血因子 Xa 抑制劑，抑制人和兔凝血因子 Xa 的 Ki 值分別為 0.08 nM 和 0.17 nM。Apixaban 正在開(kāi)發(fā)用于預(yù)防和治療各種血栓栓塞疾病 |
