產(chǎn)品編號 | D51283 |
英文名稱 | Delpazolid |
中文名稱 | 德帕唑胺 |
別 名 | MSSA/MRSA抑制劑 |
克 隆 號 | |
CAS | 1219707-39-7 |
理論分子量 | 308.31 kDa |
檢測分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus. |