產(chǎn)品編號(hào) | D51256 |
英文名稱 | Epetraborole hydrochloride |
中文名稱 | |
別 名 | 亮氨酰-tRNA 合成酶(LeuRS)抑制劑 |
克 隆 號(hào) | |
CAS | 1234563-16-6 |
理論分子量 | 273.52 kDa |
檢測(cè)分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Epetraborole, also known as GSK2251052 and AN3365, is a potent and selective leucyl-tRNA synthetase inhibitor. Epetraborole was in development for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. GSK2251052 is a novel boron-containing antibiotic that inhibits bacterial leucyl tRNA synthetase. All Clostridium perfringens strains had GSK2251052 MICs of >32 μg/ml. |