產(chǎn)品編號 | D51203 |
英文名稱 | VU 0364770 |
中文名稱 | |
別 名 | mGlu4正變構(gòu)調(diào)節(jié)劑 |
克 隆 號 | |
CAS | 61350-00-3 |
理論分子量 | 232.67 kDa |
檢測分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
VU0364770 is a Positive allosteric modulator at mGlu4 receptors (EC50 = 290 nM in mGlu4-expressing HEK 293 cells). VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease. |