| 產(chǎn)品編號 | D51199 |
| 英文名稱 | KN-62 |
| 中文名稱 | |
| 別 名 | CaMKII抑制劑 |
| 克 隆 號 | |
| CAS | 127191-97-3 |
| 理論分子量 | 721.84 kDa |
| 檢測分子量 | |
| 性 狀 | Lyophilized |
| 保存條件 | Powder: -20°C for 3 years ；In solvent: -80°C for 1 year. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
KN62 is a P2X7R antagonist (hP2X7 IC50 = 51 nM) and Ca2+/calmodulin-dependent protein kinase II inhibitor. KN62 inhibits the invasiveness of cancer cells in vitro and in vivo KN62 causes retrograde amnesia in the rat. KN62 attenuates glutamate release by inhibiting voltage-dependent Ca(2+)-channels. The effect of KN62 on Ca(2+)-influx appears to be specific to slowly-or non-inactivating conductances, and therefore presents KN62 as a potentially useful tool. |
