產(chǎn)品編號 | D51196 |
英文名稱 | R-(+)-ETOMOXIR |
中文名稱 | |
別 名 | CPT-1抑制劑 |
克 隆 號 | |
CAS | 124083-20-1 |
理論分子量 | 326.82 kDa |
檢測分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
R-(+)-ETOMOXIR is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. This prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria. This step is essential to the production of ATP from fatty acid oxidation. Etomoxir has also been identified as a direct agonist of PPARα. |