| 產(chǎn)品編號(hào) | D51176 |
| 英文名稱 | CC-930 |
| 中文名稱 | |
| 別 名 | JNK1/2/3 抑制劑 |
| 克 隆 號(hào) | |
| CAS | 899805-25-5 |
| 理論分子量 | 448.44 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
CC-930, also known as Tanzisertib, is a potent, selective, and orally active JNK inhibitor with potential antifibrotic activity. CC-930 entered Phase I clinical trials. Tanzisertib may have potential use for prevention and treatment of dermal fibrosis. Selective inhibition of JNK by CC-930 exerted potent antifibrotic effects in vitro and in different models in vivo. JNK might thus be a novel molecular target for the treatment of fibrosis in SSc. |
