| 產(chǎn)品編號 | D51175 |
| 英文名稱 | ML-329 |
| 中文名稱 | |
| 別 名 | MITF抑制劑 |
| 克 隆 號 | |
| CAS | 19992-50-8 |
| 理論分子量 | 328.34 kDa |
| 檢測分子量 | |
| 性 狀 | Lyophilized |
| 保存條件 | Store in dry, dark place for one year. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
ML-329 is an inhibitor of the microphthalmia-associated transcription factor (MITF) pathway with an IC50 value of 1.2 μM for promoter activity of the MITF target gene TRPM-1. ML-329 showed specific activity against the MITF-dependent cells, primary melanocytes but no effect on the viability in A375 cells. ML-329 reduced the expression of multiple MITF target genes, including pigment-related genes and the cell cycle regulator CDK2. As a tool compound, ML-329 will be useful in elucidating the role of MITF in melanocyte lineage development and in melanoma disease progression. |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
