| 產(chǎn)品編號(hào) | bs-4391R |
| 英文名稱 | ZMIZ2 Rabbit pAb |
| 中文名稱 | 鋅指MIZ結(jié)構(gòu)域蛋白2抗體 |
| 別 名 | 2410117E06Rik; D11Bwg0280e; DKFZp761I2123; hZIMP7; KIAA1886; PIAS like protein Zimp7; PIAS-like protein Zimp7; R74931; RGD1309256; RP23-198N14.8; ZIMP7; Zinc finger MIZ domain containing protein 2; Zinc finger MIZ domain-containing protein 2; Zinc finger MIZ type containing 2; zinc finger, MIZ-type containing 2; zinc finger, MIZtype containing2; ZMIZ 2; Zmiz2; ZMIZ2_HUMAN. |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 97 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZMIZ2: 1-100/920 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010] Function: Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. Subcellular Location: Nucleus. Detected at replication foci throughout S phase. Tissue Specificity: Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary. Similarity: Contains 1 SP-RING-type zinc finger. SWISS: Q8NF64 Gene ID: 83637 Database links: Entrez Gene: 83637 Human Entrez Gene: 52915 Mouse Omim: 611196 Human SwissProt: Q8NF64 Human SwissProt: Q8CIE2 Mouse Unigene: 600681 Human Unigene: 77978 Human Unigene: 1144 Mouse |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZMIZ2) Polyclonal Antibody, Unconjugated (bs-4391R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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