| 產(chǎn)品編號(hào) | bs-16303R |
| 英文名稱 | Rabbit Anti-GPX8 antibody |
| 中文名稱 | 谷胱甘肽過(guò)氧化物酶8抗體 |
| 別 名 | EPLA847; Glutathione peroxidase 8 (putative); Glutathione peroxidase 8; GPX 8; GPx-8; gpx8; GPX8_HUMAN; GSHPx-8; Probable glutathione peroxidase 8; UNQ847. |
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Specific References (1) | bs-16303R has been referenced in 1 publications.
[IF=1.516] Junli Liuet al. MiR-9-5p inhibits mitochondrial damage and oxidative stress in AD cell models by targeting GSK-3β. Biosci Biotechnol Biochem
. 2020 Nov;84(11):2273-2280. WB ; mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 新陳代謝 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 24kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPX8: 111-209/209 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1–8). GPx-8 (glutathione peroxidase 8), also known as GSHPx-8, is a 209 amino acid single-pass membrane protein. The gene encoding GPx-8 maps to human chromosome 5q11.2 and mouse chromosome 13 D2.2. Subcellular Location: Membrane. Similarity: Belongs to the glutathione peroxidase family. SWISS: Q8TED1 Gene ID: 493869 Database links: Entrez Gene: 493869 Human SwissProt: Q8TED1 Human Unigene: 289044 Human |
| 產(chǎn)品圖片 |
Sample: Uterus (Mouse) Lysate at 40 ug
Primary: Anti-GPX8 (bs-16303R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 24 kD
Observed band size: 26 kD
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