| 產(chǎn)品編號(hào) | bsm-61349R |
| 英文名稱(chēng) | Phospho-CDC42 (Ser71) Recombinant Rabbit mAb |
| 中文名稱(chēng) | 磷酸化細(xì)胞分化周期CDC42蛋白重組兔單抗 |
| 別 名 | CDC42; CDC42Hs; G25K; TKS; MIG5; Ras like protein TC25. |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 21 kDa |
| 檢測(cè)分子量 | 24 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Cdc42 around the phosphorylation site of S71: PL-pS-YP |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development. SWISS: P60953 Gene ID: 998 Cdc42，是細(xì)胞骨架和細(xì)胞極化的重要調(diào)節(jié)蛋白，在減數(shù)分裂和卵母細(xì)胞成熟過(guò)程中有重要的作用，尤其在細(xì)胞分化，遷移過(guò)程中起到一定的作用,目前在腫瘤研究中得到了重視。 |
| 產(chǎn)品圖片 |
Western blot analysis of (1) A431 cell lysate treated with LP; (2) A431 cell lysate. Using Phospho-CDC42 (Ser71) (bsm-61349R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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